Investigation of Balkan endemic nephropathy in Serbia: How to proceed?
نویسندگان
چکیده
منابع مشابه
Balkan Endemic Nephropathy in Serbia: Current Status and Future Research
During the 90s, wars and economic hardship hampered most attempts for serious research in Serbia, as well as in other BEN affected countries. This relative lull in intensive research provided an opportunity for identifying key problems and assessing priorities for future research. The following issues were singled out as relevant from this point of view: 1. What is the trend of BEN? Did it disa...
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Endemic nephropathy is a syndrome that comprises two entities: chronic interstitial nephropathy and urothelial cell cancers predominantly of the upper urinary tract. The etiological agent for the disease is aristolochic acid, a compound found in the plants of Aristolochia spp. The development of urothelial cancers is characterized by the formation of aristolactam DNA adducts leading to mutation...
متن کاملEarly Screening of Balkan Endemic Nephropathy
Introduction Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical implementing of in-field screening of B...
متن کاملWeathered Coal Deposits and Balkan Endemic Nephropathy
The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
متن کاملBalkan Endemic Nephropathy: an Update Renal Interstitial Fibrosis Is a Major Feature of Balkan Endemic Nephropathy (ben)
RENAL INTERSTITIAL FIBROSIS IS A MAJOR FEATURE OF BALKAN ENDEMIC NEPHROPATHY (BEN) G. A. Müller, M. Zeisberg, F Strutz Dept. of Nephrology & Rheumatology, Georg-August Universität Göttingen, 37075 Göttingen, Germany Balkan Nephropathy is a common renal disease in the Balkan region which often leads to endstage renal failure. The pathogenesis of this disease is still unknown, however, the pathwa...
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ژورنال
عنوان ژورنال: Srpski arhiv za celokupno lekarstvo
سال: 2010
ISSN: 0370-8179,2406-0895
DOI: 10.2298/sarh1004256d